Article

Potent GST ketosteroid isomerase activity relevant to ecdysteroidogenesis in the malaria vector <i>Anopheles gambiae</i>

2023-03-01

Abstract excerpt

Nobo is a glutathione transferase (GST) crucially contributing to ecdysteroid biosynthesis in insects of the orders Diptera and Lepidoptera . Ecdysone is a vital steroid hormone in insects, which governs larval molting and metamorphosis, and suppression of its synthesis has potential as a novel approach to insect growth regulation and combatting vectors of disease. In general, GSTs catalyze detoxication, whereas...

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Literature Corpus work: b7c0d8fa-5475-50aa-bffd-f4491a69dbe6
DOI: 10.1101/2023.03.01.530595

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