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Article

Clonal evolution in diffuse large B-cell lymphoma with central nervous system recurrence

5 Jan 2021

Abstract excerpt

BACKGROUND: The prognosis of patients with secondary central nervous system lymphoma (SCNSL) is poor and despite massive advances in understanding the mutational landscape of primary diffuse large B-cell lymphoma (DLBCL), the genetic comparison to SCNSL is still lacking. We therefore collected paired samples from six patients with DLBCL with available biopsies from a lymph node (LN) at primary diagnosis and the...

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PMID: 33399078
DOI: 10.1016/j.esmoop.2020.100012

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