Article
Improving the Level of the Tyrosine Biosynthesis Pathway in Saccharomyces cerevisiae through HTZ1 Knockout and Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis.
ACS synthetic biology - 15 Jan 2021
Cai Miao, Wu Yuzhen, Qi Hang, He Jiaze, Wu Zhenzhou, Xu Haijin, Qiao Mingqiang
Abstract excerpt
In recent years, many studies have been conducted on the expression of multiple aromatic compounds by Saccharomyces cerevisiae. The concentration of l-tyrosine, as a precursor of such valuable compounds, is crucial for the biosynthesis of aromatic metabolites. In this study, a novel function of HTZ1 was found to be related to tyrosine biosynthesis, which has not yet been reported. Knockout of this gene could...
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