Population Dynamics and Structural Effects at Short and Long Range Support the Hypothesis of the Selective Advantage of the G614 SARS-CoV-2 Spike Variant

Abstract excerpt

SARS-CoV-2 epidemics quickly propagated worldwide, sorting virus genomic variants in newly established propagules of infections. Stochasticity in transmission within and between countries or an actual selective advantage could explain the global high frequency reached by some genomic variants. Using statistical analyses, demographic reconstructions, and molecular dynamics simulations, we show that the globally...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to COVID-19 epidemiological studies
• Share to SARS-CoV-2 and COVID-19 Research
• Share to Viral Infections and Outbreaks Research