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Evolution of Sequence and Structure of SARS-CoV-2 Spike Protein: A Dynamic Perspective

21 Jun 2023

Abstract excerpt

Novel coronavirus (SARS-CoV-2) enters its host cell through a surface spike protein. The viral spike protein has undergone several modifications/mutations at the genomic level, through which it modulated its structure-function and passed through several variants of concern. Recent advances in high-resolution structure determination and multiscale imaging techniques, cost-effective next-generation sequencing, and...

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PMID: 37426203
DOI: 10.1021/acsomega.3c00944

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