FOXP3 rs3761548 polymorphism is associated with tacrolimus-induced acute nephrotoxicity in renal transplant patients.

doi:10.1007/s00228-016-2140-z

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Article

FOXP3 rs3761548 polymorphism is associated with tacrolimus-induced acute nephrotoxicity in renal transplant patients.

European journal of clinical pharmacology - 1 Jan 2017

Wu Zhuo, Xu Qinxia, Qiu Xiaoyan, Jiao Zheng, Zhang Ming, Zhong Mingkang

Abstract excerpt

PURPOSE: The purpose of this study was to investigate the potential impact of FOXP3 and CCDC22 gene polymorphisms on efficacy and safety of tacrolimus (TAC) in renal transplant patients. METHODS: Genetic polymorphisms were detected in 114 Chinese renal transplant patients who were on TAC-based maintenance immunosuppression and were followed up for at least 2 years. The relationships between FOXP3 rs3761547,...

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PMID: 27747372
DOI: 10.1007/s00228-016-2140-z

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FOXP3
CCDC22

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