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Article

NFATC1 genotypes affect acute rejection and long-term graft function in cyclosporine-treated renal transplant recipients.

Pharmacogenomics - 1 Mar 2017

Xu Qinxia, Qiu Xiaoyan, Jiao Zheng, Zhang Ming, Chen Jianping, Zhong Mingkang

Abstract excerpt

AIM: To investigate the effects of SNPs in the cyclophilin A/calcineurin/nuclear factor of activated T-cells (NFATs) pathway genes (PPIA, PPP3CB, PPP3R1, NFATC1 and NFATC2) on cyclosporine (CsA) efficacy in renal transplant recipients. MATERIALS & METHODS: Seventy-six tag SNPs were detected in 155 CsA-treated renal recipients with at least a 5-year follow-up. The associations of SNPs with acute rejection,...

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Source

Identifiers

PMID: 28244807
DOI: 10.2217/pgs-2016-0171

Genes

NFATC1
NFATC2
PPIA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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