Interaction between secondhand smoke exposure and IL-17 gene polymorphism in pediatric asthma.

doi:10.1080/02770903.2025.2539802

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Article

Interaction between secondhand smoke exposure and IL-17 gene polymorphism in pediatric asthma.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Nov 2025

Oztosun Berrak, Baskan Azer Kilic, Kalayci Aysel, Ozceker Deniz, Seven Mehmet, Cokugras Haluk, Sakalli Ayse Ayzit Kilinc

Abstract excerpt

BACKGROUND: Asthma is a multifactorial disease affecting approximately 300 million people worldwide. Multiple genes, environmental risk factors, and their interactions have been associated with asthma. Smoking triggers an IL-17-mediated inflammatory response. The IL-17-related inflammatory response may differ between individuals, and this difference is associated with IL-17 polymorphisms. OBJECTIVE: Our aim was...

Read the complete abstract on PubMed

Topics

Humans
Asthma
Tobacco Smoke Pollution
Interleukin-17
Male
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Child

Cotinine

Polymorphism, Single Nucleotide

Case-Control Studies

Genetic Predisposition to Disease

Gene Frequency

Genotype

Adolescent

Child, Preschool

Gene-Environment Interaction

Source

Open in PubMed

Identifiers

PMID: 40728374
DOI: 10.1080/02770903.2025.2539802

Provenance

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