Article
NAT1 genetic variation increases asthma risk in children with secondhand smoke exposure.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Mar 2021
Brooks Cassandra C, Martin Lisa J, Pilipenko Valentina, He Hua, LeMasters Grace K, Lockey James E, Bernstein David I, Ryan Patrick H, Khurana Hershey Gurjit K, Biagini Myers Jocelyn M
Abstract excerpt
OBJECTIVE: We previously reported that children exposed to secondhand smoke (SHS) that carried variants in the NAT1 gene had over two-fold higher hair cotinine levels. Our objective was to determine if NAT1 polymorphisms confer increased risk for developing asthma in children exposed to SHS. METHODS: White participants in the Cincinnati Childhood Allergy and Air Pollution Study (n = 359) were genotyped for 10...
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