Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Copy Number Analysis Reveal Genetic Risks of Penile Cancer

14 Dec 2020

Abstract excerpt

Objectives To evaluate copy number alterations (CNAs) in genes associated with penile cancer (PeC) and determine their correlation and prognostic ability with PeC. Methods Whole-exome sequencing was performed for tumor tissue and matched normal DNA of 35 patients diagnosed with penile squamous cell carcinoma from 2011 to 2016. Somatic CNAs were detected using the Genome Analysis Toolkit (GATK). Retrospective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Diagnosis and Treatment
Share to Genital Health and Disease
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33381457
DOI: 10.3389/fonc.2020.596261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Copy Number Analysis Reveal Genetic Risks of Penile CancerPMID 33381457Read ↗

Pathogenesis of Penile Squamous Cell Carcinoma: Molecular Update and Systematic Review.Semantic proximity Read ↗

Genomic profiling reveals the pivotal role of hrHPV driving copy number and gene expression alterations, including mRNA downregulation of TP53 and RB1 in penile cancerSemantic proximity Read ↗

Risk factors and molecular characterization of penile cancer: impact on prognosis and potential targets for systemic therapy.Semantic proximity Read ↗

Molecular characterization and integrative genomic analysis of a panel of newly established penile cancer cell lines.Semantic proximity Read ↗

Multidimensional integrative analysis uncovers driver candidates and biomarkers in penile carcinomaSemantic proximity Read ↗

Genomic Profiling of Human Penile Carcinoma Predicts Worse Prognosis and SurvivalSemantic proximity Read ↗

The molecular pathogenesis of penile carcinoma—current developments and understandingSemantic proximity Read ↗

Genomic Profiles and Clinical Outcomes of Penile Squamous Cell Carcinoma With Elevated Tumor Mutational BurdenSemantic proximity Read ↗

Impact of Copy Number Alterations on Human Papillomavirus (HPV)-Induced and HPV-Independent Penile Cancers.Semantic proximity Read ↗

Mutational landscape of penile squamous cell carcinoma in a Chinese populationSemantic proximity Read ↗

Mitochondrial genome analysis in penile carcinoma.Semantic proximity Read ↗

New Insights into the Molecular Profile of Penile Squamous Cell Carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.