Article
CXC Chemokine Receptor Type 5 Gene Polymorphisms in a Cohort of Egyptian Patients with Diffuse Large B-Cell Lymphoma.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2021
Makhlouf Manal Mohamed, Radwan Eman Roshdy, Khorshed Ola Mohamed, Fathi Lamees Mohamed, Elmasry Manal Mohamed
Abstract excerpt
BACKGROUND: The chemokine receptor CXCR5 is selectively expressed on B cells; it is involved in lymphocyte homing and the development of normal lymphoid tissue. Its principle ligand is CXCL13 or B lymphocyte chemoattractant. Three polymorphisms in the CXCR5 gene, rs148351692 C/G, rs6421571 C/T, and rs78440425 G/A, have been identified. OBJECTIVE: To assess the genetic polymorphisms of CXCR5 and evaluate their...
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