Article
Red panda: a novel method for detecting variants in single-cell RNA sequencing.
BMC genomics - 29 Dec 2020
Cornish Adam, Roychoudhury Shrabasti, Sarma Krishna, Pramanik Suravi, Bhakat Kishor, Dudley Andrew, Mishra Nitish K, Guda Chittibabu
Abstract excerpt
BACKGROUND: Single-cell sequencing enables us to better understand genetic diseases, such as cancer or autoimmune disorders, which are often affected by changes in rare cells. Currently, no existing software is aimed at identifying single nucleotide variations or micro (1-50 bp) insertions and deletions in single-cell RNA sequencing (scRNA-seq) data. Generating high-quality variant data is vital to the study of...
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