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Calcium intake, levels and supplementation and effect modification by genetic variation of calcium homeostasis on the risk of colorectal cancer: the Rotterdam study.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Sept 2021

Araghi Sadaf Oliai, Jayakkumaran Abi, Mulder Marlies, Stricker Bruno H, Ruiter Rikje, Kiefte-de Jong Jessica C

Abstract excerpt

OBJECTIVES: Previous studies showed that high calcium intake may be associated with the reduced colorectal cancer (CRC) risk, but results were inconclusive. In this study, we evaluated whether calcium intake from diet and supplements, as well as the calcium levels itself, were associated with the CRC risk in middle-aged and older individuals. Also, we evaluated whether these associations were modified by genetic...

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PMID: 33369946
DOI: 10.1097/CEJ.0000000000000650

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