Article
Transcription factor networks of oligodendrogliomas treated with adjuvant radiotherapy or observation inform prognosis.
Neuro-oncology - 5 May 2021
So Jonathan, Mamatjan Yasin, Zadeh Gelareh, Aldape Kenneth, Moraes Fabio Y
Abstract excerpt
BACKGROUND: Recent international sequencing efforts have allowed for the molecular taxonomy of lower-grade gliomas (LGG). We sought to analyze The Cancer Genome Atlas (TCGA, 2015) gene expression datasets on molecularly defined oligodendrogliomas (IDH-mutated and 1p/19q-codeleted) patients treated with adjuvant radiation or those observed to discover prognostic markers and pathways. METHODS: mRNA expression and...
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