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Article

Revisiting prognostic factors in glioma with leptomeningeal metastases: a comprehensive analysis of clinical and molecular factors and treatment modalities.

Journal of neuro-oncology - 1 Mar 2023

Park Yae Won, Han Kyunghwa, Kim Sooyon, Kwon Hyuk, Ahn Sung Soo, Moon Ju Hyung, Kim Eui Hyun, Kim Jinna, Kang Seok-Gu, Chang Jong Hee, Kim Se Hoon, Lee Seung-Koo

Abstract excerpt

PURPOSE: To comprehensively investigate prognostic factors, including clinical and molecular factors and treatment modalities, in adult glioma patients with leptomeningeal metastases (LM). METHODS: Total 226 patients with LM (from 2001 to 2021 among 1495 grade 2 to 4 glioma patients, 88.5% of LM patients being IDH-wildtype) with complete information on IDH mutation, 1p/19q codeletion, and MGMT promoter...

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Identifiers

PMID: 36841906
DOI: 10.1007/s11060-022-04233-y
PMCID: PMC10050057

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