Article

Temporal dynamics of radiotherapy and chemotherapy response in lower-grade gliomas using causal machine learning

2026-03-02

Abstract excerpt

Lower-grade gliomas (World Health Organization [WHO] grades 2-3) exhibit variable treatment responses, yet clinical decisions remain guided by population-level trial results. Standard causal survival forests estimate treatment effects at individual time horizons but lack methodology to synthesize these into interpretable temporal trajectories. Here, we apply the Causal Analysis of Survival Trajectories (CAST) fram...

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Literature Corpus work: 79d67018-302e-5103-bba7-4eebaf85f63e
DOI: 10.64898/2026.02.28.26347288

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