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Article

RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy

8 Dec 2020

Abstract excerpt

RAB39B is located on the X chromosome and encodes the RAB39B protein that belongs to the RAB family. Mutations in RAB39B are known to be associated with X-linked intellectual disability (XLID), Parkinson’s disease, and autism. However, the patho/physiological functions of RAB39B remain largely unknown. In the present study, we established Rab39b knockout (KO) mice, which exhibited overall normal birth rate and...

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PMID: 33364235
DOI: 10.3389/fcell.2020.598622

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