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Article

Incorporating antagonistic pleiotropy into models for molecular replicators.

Bio Systems - 1 Mar 2021

Qu Tianjiao, Calabrese Peter, Singhavi Pratik, Tower John

Abstract excerpt

In modern cells, chromosomal genes composed of DNA encode multi-subunit protein/RNA complexes that catalyze the replication of the chromosome and cell. One prevailing theory for the origin of life posits an early stage involving self-replicating macromolecules called replicators, which can be considered genes capable of self-replication. One prevailing theory for the genetics of aging in humans and other...

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Identifiers

PMID: 33359635
DOI: 10.1016/j.biosystems.2020.104333
PMCID: PMC7870564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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