Article
Increased impulsive behavior and risk proneness following lentivirus-mediated dopamine transporter over-expression in rats' nucleus accumbens.
Neuroscience - 3 Mar 2009
Adriani W, Boyer F, Gioiosa L, Macrì S, Dreyer J-L, Laviola G
Abstract excerpt
Multiple theories have been proposed for sensation seeking and vulnerability to impulse-control disorders [Zuckerman M, Kuhlman DM (2000) Personality and risk-taking: Common biosocial factors. J Pers 68:999-1029], and many of these rely on a dopamine system deficit. Available animal models reproduce only some behavioral symptoms and seem devoid of construct validity. We used lentivirus tools for over-expressing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
