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Biomarker-guided preemption of steroid-refractory graft-versus-host disease with α-1-antitrypsin

9 Dec 2020

Abstract excerpt

Steroid-refractory (SR) acute graft-versus-host disease (GVHD) remains a major cause of nonrelapse mortality (NRM) after allogeneic hematopoietic cell transplantation (HCT), but its occurrence is not accurately predicted by pre-HCT clinical risk factors. The Mount Sinai Acute GVHD International Consortium (MAGIC) algorithm probability (MAP) identifies patients who are at high risk for developing SR GVHD as early...

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PMID: 33351103
DOI: 10.1182/bloodadvances.2020003336

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