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Genetic Risk Score Enhances Coronary Artery Disease Risk Prediction in Individuals With Type 1 Diabetes.

Diabetes care - 1 Mar 2022

Lithovius Raija, Antikainen Anni A, Mutter Stefan, Valo Erkka, Forsblom Carol, Harjutsalo Valma, Sandholm Niina, Groop Per-Henrik

Abstract excerpt

OBJECTIVE: Individuals with type 1 diabetes are at a high lifetime risk of coronary artery disease (CAD), calling for early interventions. This study explores the use of a genetic risk score (GRS) for CAD risk prediction, compares it to established clinical markers, and investigates its performance according to the age and pharmacological treatment. RESEARCH DESIGN AND METHODS: This study in 3,295 individuals...

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Share to Coronary Artery Disease
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Proportional Hazards Models

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Identifiers

PMID: 35019974
DOI: 10.2337/dc21-0974

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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