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Pediatric High Grade Gliomas in the Context of Cancer Predisposition Syndromes

1 May 2018

Abstract excerpt

Germline mutations in cancer causing genes result in high risk of developing cancer throughout life. These cancer predisposition syndromes (CPS) are especially prevalent in childhood brain tumors and impact both the patient's and other family members' survival. Knowledge of specific CPS may alter the management of the cancer, offer novel targeted therapies which may improve survival for these patients, and...

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PMID: 29742882
DOI: 10.3340/jkns.2018.0031

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