Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Detection of activating mutations in RAS/RAF/MEK/ERK and JAK/STAT signaling pathways].

Terapevticheskii arkhiv - 1 Sept 2020

Zarubina K I, Parovichnikova E N, Surin V L, Pshenichnikova O S, Gavrilina O A, Isinova G A, Troitskaia V V, Sokolov A N, Gal'tseva I V, Kapranov N M, Davydova I O, Obukhova T N, Sudarikov A B, Savchenko V G

Abstract excerpt

ISSUE: The study of activating mutations (NRAS,KRAS,FLT3,JAK2,CRLF2genes) of RAS/RAF/MEK/ERK and JAK/STAT signaling pathways in B-cell acute lymphoblastic leukemia (B-ALL) in adult patients which are included in Russian multicenter clinical trials. MATERIALS AND METHODS: Within the multicenter study there were 119 adult patients included withde novoB-ALL. The study was considered as prospective and retrospective....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitogen-Activated Protein Kinase Kinases
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Russia

Source

Identifiers

PMID: 33346443
DOI: 10.26442/00403660.2020.07.000772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Detection of activating mutations in RAS/RAF/MEK/ERK and JAK/STAT signaling pathways].PMID 33346443Read ↗

[Clinical significance of analysis of BCR- ABL kinase domain mutation in chronic myeloid leukemia patients].Semantic proximity Read ↗

Impact of mutations in FLT3, PTPN11 and RAS genes on the overall survival of pediatric B cell precursor acute lymphoblastic leukemia in Brazil.Semantic proximity Read ↗

Mutational status of NRAS, KRAS, and PTPN11 genes is associated with genetic/cytogenetic features in children with B-precursor acute lymphoblastic leukemia.Semantic proximity Read ↗

[Constitutive activation of MAP kinase pathway and STAT pathway in AML].Semantic proximity Read ↗

[The Effect of KRAS on Proliferation and Apoptosis of T-ALL Cell Lines].Semantic proximity Read ↗

[Prognostic analysis of patients with mutations in the JAK/STAT signaling pathway in adult acute lymphoblastic leukemia].Semantic proximity Read ↗

Analysis of KRAS and NRAS Gene Mutations in Arab Asian Children With Acute Leukemia: High Frequency of RAS Mutations in Acute Lymphoblastic Leukemia.Semantic proximity Read ↗

[Detection of activated oncogenes in hematological malignancies using RT-PCR method and its clinical applications].Semantic proximity Read ↗

Two Transforming C-RAF Germ-Line Mutations Identified in Patients with Therapy-Related Acute Myeloid LeukemiaSemantic proximity Read ↗

[Fluorescence Quantitative PCR Detection of ABL1 Kinase Region Mutations].Semantic proximity Read ↗

[Activation of protooncogenes by point mutations in hematological malignancies].Semantic proximity Read ↗

Lack of KRAS gene mutations in chronic myeloid leukemia in Iran.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.