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[Fluorescence Quantitative PCR Detection of ABL1 Kinase Region Mutations].

Zhongguo shi yan xue ye xue za zhi - 1 Oct 2024

Cheng Huan-Chen, Li Si, Wang Dian-Zhi, Liu Yu, Gong Tie-Jun, Ma Jun

Abstract excerpt

OBJECTIVE: To establish a highly sensitive and quantitative detection method for ABL1 kinase region mutations, provide strong support for the early diagnosis and treatment of chronic myeloid leukemia(CML). METHODS: Sampele from 35 CML patients who were initially tested negative for ABL1 kinase region mutations by Sanger sequencing were collected. The ABL1 kinase region mutation was detected by the fluorescence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39479819
DOI: 10.19746/j.cnki.issn.1009-2137.2024.05.011

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