Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience.

doi:10.3389/fimmu.2020.605688

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience.

Frontiers in immunology - 1 Jan 2020

Littera Roberto, Campagna Marcello, Deidda Silvia, Angioni Goffredo, Cipri Selene, Melis Maurizio, Firinu Davide, Santus Simonetta, Lai Alberto, Porcella Rita, Lai Sara, Rassu Stefania, Scioscia Rosetta, Meloni Federico, Schirru Daniele, Cordeddu William, Kowalik Marta Anna, Serra Maria, Ragatzu Paola, Carta Mauro Giovanni, Del Giacco Stefano, Restivo Angelo, Deidda Simona, Orrù Sandro, Palimodde Antonella, Perra Roberto, Orrù Germano, Conti Maria, Balestrieri Cinzia, Serra Giancarlo, Onali Simona, Marongiu Francesco, Perra Andrea, Chessa Luchino

Abstract excerpt

Aim: SARS-CoV-2 infection is a world-wide public health problem. Several aspects of its pathogenesis and the related clinical consequences still need elucidation. In Italy, Sardinia has had very low numbers of infections. Taking advantage of the low genetic polymorphism in the Sardinian population, we analyzed clinical, genetic and immunogenetic factors, with particular attention to HLA class I and II molecules,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COVID-19

Share to Gene Frequency

Share to Histocompatibility Antigens Class I

Share to HLA-DRB1 Chains

Share to Immunogenetics

Share to Italy

Share to SARS-CoV-2

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 33343579
DOI: 10.3389/fimmu.2020.605688
PMCID: PMC7746644

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience.PMID 33343579Read ↗

Bioinformatic HLA Studies in the Context of SARS-CoV-2 Pandemic and Review on Association of HLA Alleles with Preexisting Medical Conditions.Semantic proximity Read ↗

HLA repertoire of 115 UAE nationals infected with SARS-CoV-2.Semantic proximity Read ↗

Natural killer-cell immunoglobulin-like receptors trigger differences in immune response to SARS-CoV-2 infection.Semantic proximity Read ↗

Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphismsSemantic proximity Read ↗

HLA and AB0 Polymorphisms May Influence SARS-CoV-2 Infection and COVID-19 Severity.Semantic proximity Read ↗

Possible role of HLA class-I genotype in SARS-CoV-2 infection and progression: A pilot study in a cohort of Covid-19 Spanish patients.Semantic proximity Read ↗

HLA Genotypes in Patients with Infection Caused by Different Strains of SARS-CoV-2.Semantic proximity Read ↗

HLA-C*04:01 Affects HLA Class I Heterozygosity and Predicted Affinity to SARS-CoV-2 Peptides, and in Combination With Age and Sex of Armenian Patients Contributes to COVID-19 SeveritySemantic proximity Read ↗

Influence of HLA gene polymorphisms on susceptibility and outcome post infection with the SARS-CoV virusSemantic proximity Read ↗

Lack of association between HLA‐A, ‐B and ‐DRB1 alleles and the development of SARS: a cohort of 95 SARS‐recovered individuals in a population of Guangdong, southern ChinaSemantic proximity Read ↗

The genetic basis of the immune response to SARS-CoV-2 infection and vaccination in the Italian municipality of Vo'.Semantic proximity Read ↗

Immunogenetic studies in SARS: developing a clinical prognostic profile for severe diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.