Asymptomatic SARS-CoV-2 Infection: Association Involving the HLA-B*15 Allele Group in Brazilian Individuals.

doi:10.1111/tan.70262

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Asymptomatic SARS-CoV-2 Infection: Association Involving the HLA-B*15 Allele Group in Brazilian Individuals.

HLA - 1 Jun 2025

Ayo Christiane Maria, Magalhães Henrique, Miola Marcos Paulo, Brandão Cinara Cássia, Nogueira Maurício Lacerda, Estofolete Cássia Fernanda, de Souza Victor Hugo, Visentainer Jeane Eliete Laguila, de Mattos Luiz Carlos

Abstract excerpt

The aim of this study was to investigate the influence of HLA-A, -B and -C polymorphisms on the clinical course of SARS-CoV-2 infection and on the progression of COVID-19 in a population from southeastern Brazil. This study included 478 unvaccinated individuals. Of these, 369 were hospitalised with critical/severe (n = 309) or moderate/mild (n = 60) symptoms, and 109 were asymptomatic. The control group consisted...

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Topics

Humans
COVID-19
Brazil
SARS-CoV-2
Male
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Alleles

Adult

HLA-B15 Antigen

Genetic Predisposition to Disease

Asymptomatic Infections

Aged

Polymorphism, Genetic

Source

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Identifiers

PMID: 40451247
DOI: 10.1111/tan.70262
PMCID: PMC12127060

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