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Article

GWAS links variants in neuronal development and actin remodeling related loci with pseudoexfoliation syndrome without glaucoma.

Experimental eye research - 1 Mar 2018

Zagajewska Katarzyna, Piątkowska Magdalena, Goryca Krzysztof, Bałabas Aneta, Kluska Anna, Paziewska Agnieszka, Pośpiech Ewelina, Grabska-Liberek Iwona, Hennig Ewa E

Abstract excerpt

Pseudoexfoliation syndrome (PEXS) is an age-related elastosis, strongly associated with the development of secondary glaucoma. It is clearly suggested that PEXS has a genetic component, but this has not been extensively studied. Here, a genome-wide association study (GWAS) using a DNA-pooling approach was conducted to explore the potential association of genetic variants with PEXS in a Polish population,...

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Source

Identifiers

PMID: 29278698
DOI: 10.1016/j.exer.2017.12.006

Genes

LOXL1
CADM2
FGF14
FMN1
RBFOX1
SORBS2
TNIK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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