Article
Fetal gastroschisis: Maternal and fetal methylation profile.
Prenatal diagnosis - 1 Mar 2021
Freitas Amanda Brasil de, Francisco Rossana Pulcineli Vieira, Centofanti Sandra Frankfurt, Damasceno Jullian Gabriel, Chehimi Samar Nasser, Osmundo-Junior Gilmar de Souza, Kulikowski Leslie Domenici, Brizot Maria de Lourdes
Abstract excerpt
OBJECTIVE: The purpose of this study was to describe the genomic deoxyribonucleic acid (DNA) methylation profile in fetuses with gastroschisis, determine whether the profile was inherited, and investigate any possible correlations with maternal risk factors. METHOD: Genome-wide DNA methylation analysis of 96 blood samples was performed using the Illumina Human Methylation 850K BeadChip. The blood samples were...
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