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Article

DNA methylation profiling of placental villi from karyotypically normal miscarriage and recurrent miscarriage.

The American journal of pathology - 1 Jun 2013

Hanna Courtney W, McFadden Deborah E, Robinson Wendy P

Abstract excerpt

Miscarriage occurs in 15% of clinical pregnancies. Although chromosomal errors are observed in >50%, causes of karyotypically normal losses are poorly understood. DNA methylation undergoes reprogramming during development and must be appropriately set to maintain a healthy pregnancy. We hypothesize that aberrant DNA methylation may cause karyotypically normal miscarriage, particularly among women experiencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23583422
DOI: 10.1016/j.ajpath.2013.02.021

Genes

AXL
DEFB1
IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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