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Low High-Density Lipoprotein Cholesterol and High White Blood Cell Counts: A Mendelian Randomization Study.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2021

Harsløf Mads, Pedersen Kasper M, Nordestgaard Børge G, Afzal Shoaib

Abstract excerpt

OBJECTIVE: Animal studies suggest that HDL (high-density lipoprotein) regulates proliferation and differentiation of hematopoietic stem cells. Using a Mendelian randomization approach, we tested the hypothesis that low HDL cholesterol is associated with high white blood cell counts. Approach and Results: We included 107 952 individuals aged 20 to 100 years from the Copenhagen General Population Study with...

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Identifiers

PMID: 33327746
DOI: 10.1161/ATVBAHA.120.314983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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