Article
White Blood Cells and Blood Pressure: A Mendelian Randomization Study.
Circulation - 21 Apr 2020
Siedlinski Mateusz, Jozefczuk Ewelina, Xu Xiaoguang, Teumer Alexander, Evangelou Evangelos, Schnabel Renate B, Welsh Paul, Maffia Pasquale, Erdmann Jeanette, Tomaszewski Maciej, Caulfield Mark J, Sattar Naveed, Holmes Michael V, Guzik Tomasz J
Abstract excerpt
BACKGROUND: High blood pressure (BP) is a risk factor for cardiovascular morbidity and mortality. While BP is regulated by the function of kidney, vasculature, and sympathetic nervous system, recent experimental data suggest that immune cells may play a role in hypertension. METHODS: We studied the relationship between major white blood cell types and blood pressure in the UK Biobank population and used Mendelian...
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