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Article

Minocycline prevents the inflammatory response after retinal detachment, where microglia phenotypes being regulated through A20.

Experimental eye research - 1 Feb 2021

Gao Wenna, Du Jiantong, Chi Ying, Zhu Ruilin, Gao Xinran, Yang Liu

Abstract excerpt

Retinal detachment (RD) is a severe sight-threatening complication that can be caused by a multitude of retinal diseases. It has been evidenced that minocycline exerts neuroprotective effects by targeting microglia in the pathogenesis of massive ocular lesions including RD, but mechanisms remain elusive. We carried out this research to elucidate the potential mediators that link RD-induced vision loss with...

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Source

Identifiers

PMID: 33326811
DOI: 10.1016/j.exer.2020.108403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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