Article
The prevalence and characterisation of TRAF3 and POT1 mutations in canine B-cell lymphoma.
Veterinary journal (London, England : 1997) - 1 Dec 2020
Smith P A D, Waugh E M, Crichton C, Jarrett R F, Morris J S
Abstract excerpt
The genetic and mutational basis of canine lymphoma remains poorly understood. Several genes, including TRAF3 and POT1, are mutated in canine B-cell lymphoma (cBCL), and are likely involved in the pathogenesis of this disease. The purpose of this study was to assess the prevalence of TRAF3 and POT1 mutations in a cohort of dogs with cBCL, compared to dogs with non-cBCL diseases (including four dogs with T-cell...
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