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Article

The Genetic and Molecular Basis for Canine Models of Human Leukemia and Lymphoma

24 Jan 2020

Abstract excerpt

Emerging details of the gene expression and mutational features of canine lymphoma and leukemia demonstrate areas of similarities and differences between disease subsets in the humans and dogs. Many features of canine diffuse large B-cell lymphoma resemble the ABC form of human DLBCL, including constitutive activation of the NF-kB pathway and almost universal presence of double expressing MYC/BCL2 lymphomas....

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PMID: 32038991
DOI: 10.3389/fonc.2020.00023

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