Article
Dual delivery of IL-10 and AT-RvD1 from PEG hydrogels polarize immune cells towards pro-regenerative phenotypes.
Biomaterials - 1 Jan 2021
Sok Mary Caitlin P, Baker Nusaiba, McClain Claire, Lim Hong Seo, Turner Thomas, Hymel Lauren, Ogle Molly, Olingy Claire, Palacios Joshua I, Garcia José R, Srithar Krithik, García Andrés J, Qiu Peng, Botchwey Edward A
Abstract excerpt
Inflammation after traumatic injury or surgical intervention is both a protective tissue response leading to regeneration and a potential cause of wound complications. One potentially successful strategy to harness to pro-regenerative roles of host inflammation is the localized delivery of bioactive materials to induce immune suppressive cellular responses by cells responding to injury. In this study, we designed...
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