Article
ANOVA-HD: Analysis of variance when both input and output layers are high-dimensional.
PloS one - 1 Jan 2020
de Los Campos Gustavo, Pook Torsten, Gonzalez-Reymundez Agustin, Simianer Henner, Mias George, Vazquez Ana I
Abstract excerpt
Modern genomic data sets often involve multiple data-layers (e.g., DNA-sequence, gene expression), each of which itself can be high-dimensional. The biological processes underlying these data-layers can lead to intricate multivariate association patterns. We propose and evaluate two methods to determine the proportion of variance of an output data set that can be explained by an input data set when both data...
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