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Article

Inferring genetic architecture of complex traits using Bayesian integrative analysis of genome and transcriptome data.

BMC genomics - 5 Sept 2012

Ehsani Alireza, Sørensen Peter, Pomp Daniel, Allan Mark, Janss Luc

Abstract excerpt

BACKGROUND: To understand the genetic architecture of complex traits and bridge the genotype-phenotype gap, it is useful to study intermediate -omics data, e.g. the transcriptome. The present study introduces a method for simultaneous quantification of the contributions from single nucleotide polymorphisms (SNPs) and transcript abundances in explaining phenotypic variance, using Bayesian whole-omics models....

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Identifiers

PMID: 22950759
DOI: 10.1186/1471-2164-13-456
PMCID: PMC3543188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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