Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting Microglia for Therapy of Parkinson's Disease by Using Biomimetic Ultrasmall Nanoparticles.

Journal of the American Chemical Society - 30 Dec 2020

Liu Hanghang, Han Yaobao, Wang Tingting, Zhang Hao, Xu Qi, Yuan Jiaxin, Li Zhen

Abstract excerpt

Microglia as an important type of innate immune cell in the brain have been considered as an effective therapeutic target for the treatment of central nervous degenerative diseases. Herein, we report cell membrane coated novel biomimetic Cu2-xSe-PVP-Qe nanoparticles (denoted as CSPQ@CM nanoparticles, where PVP is poly(vinylpyrrolidone), Qe is quercetin, and CM is the cell membrane of neuron cells) for effectively...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dopamine
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microglia

Share to Nanoparticles

Share to Parkinson Disease

Share to Particle Size

Share to Vascular Cell Adhesion Molecule-1

Source

Identifiers

PMID: 33315369
DOI: 10.1021/jacs.0c09390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting Microglia for Therapy of Parkinson's Disease by Using Biomimetic Ultrasmall Nanoparticles.PMID 33315369Read ↗

Custom-Made Ceria Nanoparticles Show a Neuroprotective Effect by Modulating Phenotypic Polarization of the Microglia.Semantic proximity Read ↗

Circulating extracellular vesicles drive microglial senescence and neurodegeneration in Parkinson’s diseaseSemantic proximity Read ↗

Transition Metal Dichalcogenide Nanoflowers Rescue Immune Cells from the Cytotoxic Effects of Amyloid AggregatesSemantic proximity Read ↗

Using Extracellular Vesicles Released by GDNF-transfected Macrophages for Therapy of Parkinson’s DiseaseSemantic proximity Read ↗

Ceftriaxone affects ferroptosis and alleviates glial cell activation in Parkinson's diseaseSemantic proximity Read ↗

Advanced Therapies for Traumatic Central Nervous System Injury: Delivery Strategy Reinforced Efficient Microglial Manipulation.Semantic proximity Read ↗

In vivo nanoneurotoxicity screening using oxidative stress and neuroinflammation paradigms.Semantic proximity Read ↗

Bioactive Co-assembly of PSA/dit-VES Nanomicelles Orchestrates Macrophage Reprogramming for Acute Lung Injury TherapySemantic proximity Read ↗

Immunomodulatory mechanisms of submicron phosphatidylserine-exposing polymeric particles (PSPs)Semantic proximity Read ↗

Targeted exosome coating gene-chem nanocomplex as “nanoscavenger” for clearing α-synuclein and immune activation of Parkinson’s diseaseSemantic proximity Read ↗

Targeting Microglia Via Nanotechnology: A Novel Strategy to Overcome Neuroinflammation in Major Depressive DisorderSemantic proximity Read ↗

Microplastics and Their Effect on Neuroglia: A Narrative ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.