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Serum levels and genetic variation of IL-35 are associated with multiple sclerosis: a population-based case-control study.

Immunologic research - 1 Feb 2022

Eslami Mina, Rafiei Alireza, Baghbanian Seyed Mohammad, Fattahi Sadegh, Yazdani Zahra, Valadan Reza, Kardan Mostafa

Abstract excerpt

This study aimed to investigate the association between serum levels and polymorphic variants of IL-35 with susceptibility, clinical features, and disease severity in multiple sclerosis (MS) patients.This case-control study recruited 186 MS patients and 195 sex- and age-matched healthy controls. Serum levels and polymorphic variants of IL-35 were determined by ELISA and restriction fragment length polymorphism...

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PMID: 34708312
DOI: 10.1007/s12026-021-09246-9

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