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Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory?

BMC pulmonary medicine - 5 Apr 2016

Demarche Sophie, Schleich Florence, Henket Monique, Paulus Virginie, Van Hees Thierry, Louis Renaud

Abstract excerpt

BACKGROUND: The technique of induced sputum has allowed to subdivide asthma patients into inflammatory phenotypes according to their level of granulocyte airway infiltration. There are very few studies which looked at detailed sputum and blood cell counts in a large cohort of asthmatics divided into inflammatory phenotypes. The purpose of this study was to analyze sputum cell counts, blood leukocytes and systemic...

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C-Reactive Protein
Eosinophils
Fibrinogen
Granulocytes
Leukocyte Count

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PMID: 27044366
DOI: 10.1186/s12890-016-0208-2
PMCID: PMC4820945

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