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Article

Association of genetically predicted blood sucrose with coronary heart disease and its risk factors in Mendelian randomization.

Scientific reports - 9 Dec 2020

Zhang Ting, Au Yeung Shiu Lun, Schooling C Mary

Abstract excerpt

We assessed the associations of genetically instrumented blood sucrose with risk of coronary heart disease (CHD) and its risk factors (i.e., type 2 diabetes, adiposity, blood pressure, lipids, and glycaemic traits), using two-sample Mendelian randomization. We used blood fructose as a validation exposure. Dental caries was a positive control outcome. We selected genetic variants strongly (P < 5 × 10-6) associated...

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Identifiers

PMID: 33299099
DOI: 10.1038/s41598-020-78685-5
PMCID: PMC7725802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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