Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ZNF750–RAC1 axis as potential prognostic factor for breast cancer

29 Nov 2020

Abstract excerpt

The human zinc finger (C2H2-type) protein ZNF750 is a transcription factor regulated by p63 that plays a critical role in epithelial tissues homoeostasis, as well as being involved in the pathogenesis of cancer. Indeed, missense mutations, truncation and genomic deletion have been found in oesophageal squamous cell carcinoma. In keeping, we showed that ZNF750 negatively regulates cell migration and invasion in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Cancer-related Molecular Pathways
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33298895
DOI: 10.1038/s41420-020-00371-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ZNF750–RAC1 axis as potential prognostic factor for breast cancerPMID 33298895Read ↗

Zinc finger protein 639 expression is a novel prognostic determinant in breast cancerSemantic proximity Read ↗

The critical role of the ZNF217 oncogene in promoting breast cancer metastasis to the bone.Semantic proximity Read ↗

ZNF500 suppresses the proliferation of breast cancer cells and sensitizes them to chemotherapy by stabilizing p53 in a manner that is competitive to MDM2Semantic proximity Read ↗

ZNF703 promotes triple-negative breast cancer cells through cell-cycle signaling and associated with poor prognosisSemantic proximity Read ↗

A clinical, biologic and mechanistic analysis of the role of ZNF692 in cervical cancerSemantic proximity Read ↗

Mutational and Expression Profile of ZNF217, ZNF750, ZNF703 Zinc Finger Genes in Kenyan Women Diagnosed with Breast CancerSemantic proximity Read ↗

ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor cell invasionSemantic proximity Read ↗

A commentary on Analysis of ZNF350/ZBRK1 promoter variants and breast cancer susceptibility in non-BRCA1/2 French Canadian breast cancer families.Semantic proximity Read ↗

ZNF326 promotes malignant phenotype of glioma by up-regulating HDAC7 expression and activating Wnt pathwaySemantic proximity Read ↗

CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1Semantic proximity Read ↗

Correlation between ZBRK1/ZNF350 gene polymorphism and breast cancer.Semantic proximity Read ↗

ZNF750 is a lineage-specific tumour suppressor in squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.