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Article

NRBP1 promotes malignant phenotypes of glioblastoma by regulating PI3K/Akt activation.

Cancer medicine - 1 Aug 2024

Zhang Anli, Peng Shichao, Sun Sibai, Ye Shan, Zhao Ye, Wu Qiang

Abstract excerpt

OBJECTIVES: Glioblastoma (GBM) is the most aggressive of intracranial gliomas. Despite the maximal treatment intervention, the median survival rate is still about 14-16 months. Nuclear receptor-binding protein 1 (NRBP1) has a potential growth-promoting role on biology function of cells. In this study, we investigated whether NRBP1 promotes GBM malignant phenotypes and the potential mechanisms. METHODS: The...

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Identifiers

PMID: 39149873
DOI: 10.1002/cam4.70100
PMCID: PMC11327863

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