Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune responsive gene 1, a novel oncogene, increases the growth and tumorigenicity of glioma

10 Sept 2014

Abstract excerpt

Immune responsive gene 1 (IRG1) is highly expressed in mammalian macrophages during inflammation. However, the role of IRG1 in tumorigenesis remains unclear. In the present study, we aimed to clarify the epigenetic regulation and biological functions of IRG1 in glioma. We found that the expression level of IRG1 influenced the WHO stage in 140 glioma patients. Overexpression of IRG1 increased the growth, invasion,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Glioma Diagnosis and Treatment
Share to Immune cells in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25216059
DOI: 10.3892/or.2014.3474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune responsive gene 1, a novel oncogene, increases the growth and tumorigenicity of gliomaPMID 25216059Read ↗

MUL1, an Immune Chemokine-Related Gene, Regulates Glioma Cell Proliferation and Migration: Insights from Functional and Mechanistic StudiesSemantic proximity Read ↗

ISG20 promotes local tumor immunity and contributes to poor survival in human gliomaSemantic proximity Read ↗

Transcription Factor ELF1 Activates MEIS1 Transcription and Then Regulates the GFI1/FBW7 Axis to Promote the Development of GliomaSemantic proximity Read ↗

Prognostic and predictive value of FCER1G in glioma outcomes and response to immunotherapySemantic proximity Read ↗

Interferon regulatory factor transcript levels correlate with clinical outcomes in human gliomaSemantic proximity Read ↗

IRF7 as an Immune-Related Prognostic Biomarker and Associated with Tumor Microenvironment in Low-Grade GliomaSemantic proximity Read ↗

FLI1 enhances the malignant phenotype of glioma cells and exerts immunomodulatory effects through feedback crosstalk with exonic circRNA FECR1 and interferon‑induced ISG15.Semantic proximity Read ↗

Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cellsSemantic proximity Read ↗

LRIG1 regulates invasion and migration of human gliomas through SNAI2 and E-cadherinSemantic proximity Read ↗

ELF1 upregulates MEIS1 to accelerate proliferation, migration and invasion of glioma cells through the GFI1/FBW7 axisSemantic proximity Read ↗

Retinol binding protein 1‐dependent activation of NF‐ κB signaling enhances the malignancy of non‐glioblastomatous diffuse gliomasSemantic proximity Read ↗

Early growth response 1 promoted the invasion of glioblastoma multiforme by elevating HMGB1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.