Article
[Senotherapy: Advances and new clinical perspectives].
Medecine sciences : M/S - 1 Dec 2020
Veret Damien, Brondello Jean-Marc
Abstract excerpt
Cellular senescence has been now shown to be at the root of many degenerative processes that characterize ageing. Thus, in addition to an irreversible proliferative arrest following various stresses or inappropriate stimuli, cellular senescence leads to genetic, epigenetic, metabolic, structural and functional adaptations of the cell. Moreover, senescence phenotype spreads to the surrounding tissue through a...
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