Article
Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats.
PloS one - 1 Jan 2020
Sajko Sara, Grishkovskaya Irina, Kostan Julius, Graewert Melissa, Setiawan Kim, Trübestein Linda, Niedermüller Korbinian, Gehin Charlotte, Sponga Antonio, Puchinger Martin, Gavin Anne-Claude, Leonard Thomas A, Svergun Dimitri I, Smith Terry K, Morriswood Brooke, Djinovic-Carugo Kristina
Abstract excerpt
MORN (Membrane Occupation and Recognition Nexus) repeat proteins have a wide taxonomic distribution, being found in both prokaryotes and eukaryotes. Despite this ubiquity, they remain poorly characterised at both a structural and a functional level compared to other common repeats. In functional terms, they are often assumed to be lipid-binding modules that mediate membrane targeting. We addressed this putative...
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