Article
A Toxoplasma MORN1 null mutant undergoes repeated divisions but is defective in basal assembly, apicoplast division and cytokinesis.
PloS one - 19 Aug 2010
Lorestani Alexander, Sheiner Lilach, Yang Kevin, Robertson Seth D, Sahoo Nivedita, Brooks Carrie F, Ferguson David J P, Striepen Boris, Gubbels Marc-Jan
Abstract excerpt
The membrane occupation and recognition nexus protein 1 (MORN1) is highly conserved among apicomplexan parasites and is associated with several structures that have a role in cell division. Here we dissected the role of MORN1 using the relatively simple budding process of Toxoplasma gondii as a model. Ablation of MORN1 in a conditional null mutant resulted in pronounced defects suggesting a central role for MORN1...
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