Article
Presence of allele CYP3A4*16 does not have any bearing on carbamazepine-induced adverse drug reactions in North Indian people with epilepsy.
Indian journal of pharmacology - 1 Jan 2000
Garg Vivek Kumar, Goyal Manoj Kumar, Khullar Madhu, Saikia Biman, Medhi Bikash, Prakash Ajay, Prabhat Nandita, Tandyala Naresh, Mahesh Karthik Vinay, Kharbanda Parampreet S, Prabhakar Sudesh, Modi Manish, Lal Vivek, Shree Ritu, Sachdeva Julie
Abstract excerpt
OBJECTIVES: The objectives of this study were to determine the relationship between genetic polymorphisms in gene encodings for CYP3A4 and carbamazepine (CBZ)-induced dose-related side effects in North Indian people with epilepsy. PATIENTS AND METHODS: The current prospective study included 37 patients with CBZ-induced dose-related side effects and 102 patients who did not experience side effects while on CBZ....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.