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Article

CYP1A2 genotype affects carbamazepine pharmacokinetics in children with epilepsy.

European journal of clinical pharmacology - 1 Apr 2016

Djordjevic Natasa, Milovanovic Dragana Dragas, Radovanovic Marija, Radosavljevic Ivan, Obradovic Slobodan, Jakovljevic Mihajlo, Milovanovic Dragan, Milovanovic Jasmina R, Jankovic Slobodan

Abstract excerpt

PURPOSE: The purpose of this study is to investigate the effect of two of the most important functional CYP1A2 variations -3860G > A and -163C > A on carbamazepine pharmacokinetics in Serbian pediatric epileptic patients. METHODS: The study involved 40 Serbian pediatric epileptic patients on steady-state carbamazepine treatment. Genotyping for -3860G > A and -163C > A was carried out using PCR-RFLP method, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Source

Identifiers

PMID: 26762380
DOI: 10.1007/s00228-015-2006-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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