Article
SHROOM3, the gene associated with chronic kidney disease, affects the podocyte structure.
Scientific reports - 3 Dec 2020
Matsuura Ryo, Hiraishi Atsuko, Holzman Lawrence B, Hanayama Hiroki, Harano Koji, Nakamura Eiichi, Hamasaki Yoshifumi, Doi Kent, Nangaku Masaomi, Noiri Eisei
Abstract excerpt
Chronic kidney disease is a public health burden and it remains unknown which genetic loci are associated with kidney function in the Japanese population, our genome-wide association study using the Biobank Japan dataset (excluding secondary kidney diseases, such as diabetes mellitus) clearly revealed that almost half of the top 50 single nucleotide polymorphisms associated with estimated glomerular filtration...
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